Transcendence is a nethack-like 2d space shooter. Arrow keys to move, space and shift to fire main weapons and missiles, standard stuff.
Fullartin from the Whitty's Minecraft server introduced me and I fell in love at the words "It's like Freelancer in 2d".
It's damn hard at first but once you get going it's a lot of fun. Read the readme.html, the hotkeys are in there.
Screenshots if you be wanting them
They have a screensaver version too, in case you want some spaceships battling it out on your screen when you're not around.