Okay, i run CC on mac OSX for starters and it's never given me a problem i can't fix. I'm not running any mods that i wasn't when it was working perfectly before.

I start up the program and no commands work. it doesn't recognize anything from my keyboard, nor does it pick up anything i do with the mouse. I can't quit or skip the opening cinematic. In the middle of the opening cinematic it crashes. The abortscreen.bmp doesn't update.

Any ideas?

Try reinstalling, other than that theres nothing I can think of.