Whenever I'm halfway through a skirmish or the zombie mission, CC will randomly freeze and I'll have to use Ctrl + Alt + Dlt to close the game. Does anyone have an explanation for why this happens?

i get the same thing! except mine freezes when an enemy lands in skirmish. i think it might have something to do with my enemies always using the telepod. Which is weird because according to what i remember, i downloaded that as a mod.

I found a fix for it, just simply re-install the game. Make sure to delete your Cortex Command folder though.